Which management step is appropriate when intracranial hypertension persists despite medical therapy?

Proceed to decompressive craniectomy

When intracranial pressure remains high despite optimized medical therapy, the brain needs more space to accommodate the swelling. Decompressive craniectomy surgically removes a portion of the skull, giving the swollen brain room to expand outward and thereby lowering the pressure. This intervention directly addresses the persistent elevation that medical measures cannot control, and it can reduce the risk of herniation and improve survival in selected patients with diffuse edema. It’s considered after careful patient selection and when medical therapies have been maximized, because while it can lower ICP, it also carries risks and can result in disability among survivors. Continuing medical therapy without escalation or simply observing would not correct the ongoing high pressure and could allow deterioration, so they are not appropriate next steps in this scenario.

Continue medical therapy without escalation

Do nothing

Observe without intervention

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