What serum sodium range is generally targeted in TBI management?

What serum sodium range is generally targeted in TBI management?

• A. 120-130
• B. 100-110
• C. 135-145 mEq/L
• D. 150-160

Answer: (C)

In managing moderate to severe TBI, keeping serum sodium in the normal range helps control brain edema while preserving cerebral perfusion. Hyponatremia lowers serum osmolality, encouraging water into brain tissue and can worsen intracranial pressure and outcomes. Hypernatremia raises osmolality, which can help reduce ICP acutely but carries risks if maintained long-term. Therefore, the typical target is a normal sodium level, around 135-145 mEq/L, to balance edema control with stable cerebral perfusion. Values well below this range or above it are not desirable for routine management, as they’re associated with complications and worse outcomes.

In managing moderate to severe TBI, keeping serum sodium in the normal range helps control brain edema while preserving cerebral perfusion. Hyponatremia lowers serum osmolality, encouraging water into brain tissue and can worsen intracranial pressure and outcomes. Hypernatremia raises osmolality, which can help reduce ICP acutely but carries risks if maintained long-term. Therefore, the typical target is a normal sodium level, around 135-145 mEq/L, to balance edema control with stable cerebral perfusion. Values well below this range or above it are not desirable for routine management, as they’re associated with complications and worse outcomes.